Synthesis and anticancer and anti-HIV testing of some pyrazino [1, 2-a] benzimidazole derivatives
Ş Demirayak, UA Mohsen, AÇ Karaburun
Index: Demirayak, Seref; Abu Mohsen, Usama; Cagri Karaburun, Ahmet European Journal of Medicinal Chemistry, 2002 , vol. 37, # 3 p. 255 - 260
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Citation Number: 128
Abstract
In this study, some 1-methylene-2, 3-diaryl-1, 2-dihydropyrazino [1, 2-a] benzimidazole and some 1-(2-arylvinyl)-3-arylpyrazino [1, 2-a] benzimidazole derivatives were synthesised. The structure elucidation of the compounds was performed by IR, 1H-NMR and MASS spectroscopic data and elemental analyses results. Anticancer and anti-HIV activities of the compounds were examined, however no anti-HIV activity was seen; highly notable ...
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