Amination of halopyridines on KF-alumina under microwave irradiation
DH Yang, BY Yang, ZC Chen…
Index: Yang, De-Hong; Yang, Ben-Yong; Chen, Zhen-Chu; Chen, Song-Ying Journal of Chemical Research, 2006 , # 9 p. 600 - 601
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Abstract
Pyridine-2-amine is an important class of synthetic intermediates in organic synthesis, and many compounds can be synthesised with them that display biological and pharmaceutical activities. Their derivatives are often used as ligands in coordination and organometallic chemistry, and now have found industrial applications as fluorescent dyes. 1 The earlier preparations of aminopyridines which involve aromatic nucleophilic substitution by SNAr, ...
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