One-Pot Synthesis of 3, 4-Dihydropyrimidin-2 (1 H)-ones and Their Sulfur Derivatives with H2SO4 Supported on Silica Gel or Alumina

KA Dilmaghani, B Zeynizadeh…

Index: Dilmaghani, Karim Akbari; Zeynizadeh, Behzad; Yari, Mahdi Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 7 p. 1722 - 1728

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Citation Number: 8

Abstract

The one-pot condensation of aromatic aldehydes, β-dicarbonyl compounds, and urea or thiourea in the presence of H2SO4 supported on silica gel or alumina (80% m/m) in refluxing n-hexane produces 3, 4-dihydropyrimidin-2 (1 H)-ones and their sulfur derivatives in high to excellent yields.

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