Synthesis of new building blocks for peptide nucleic acids containing monomers with variations in the backbone

S Jordan, C Schwemler, W Kosch, A Kretschmer…

Index: Jordan, Stephan; Schwemler, Christoph; Kosch, Winfried; Kretschmer, Axel; Schwenner, Eckhardt; Stropp, Udo; Mielke, Burkhard Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 6 p. 681 - 686

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Citation Number: 39

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... New PNA monomers containing aminoprolines or pyrrolidines as backbones have been synthesized. Oligomerisation was carried out on a solid support. Resistance to enzymatic degradation was tested. ... The synthesis of various new building blocks for PNAs eg with a backbone ...