The importance of the ortho effect in the solvolyses of 2, 6??difluorobenzoyl chloride
KH Park, DN Kevill
Index: Park, Kyoung-Ho; Kevill, Dennis N. Journal of Physical Organic Chemistry, 2012 , vol. 25, # 3 p. 267 - 270
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Citation Number: 5
Abstract
Abstract The ortho effect of the chloro substituents in 2, 6-dichlorobenzoyl chloride sufficiently hindered attack on the acyl carbon such that an ionization mechanism was observed over the full range of solvents studied. We now compare this behavior with that of 2, 6-difluorobenzoyl chloride. The smaller fluoro substituents allow the dominant pathway to be addition–elimination (association–dissociation) in all solvents except those rich in ...
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