Wake-promoting agents: Search for next generation modafinil: Part IV

P Louvet, D Schweizer, ME Gourdel, E Riguet…

Index: Louvet, Philippe; Schweizer, Dominique; Gourdel, Marie-Edith; Riguet, Eric; Yue, Christoph; Marcy, Val R.; Lin, Yin Guo; Gruner, John; Lesur, Brigitte; Bacon, Edward R.; Chatterjee, Sankar European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 949 - 951

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Abstract

In search of a next generation molecule to the novel wake promoting agent modafinil, a series of diphenyl ether derived wakefulness enhancing agents (in rat) was developed. From this work, racemic compound 16 was separated into its chiral enantiomers to profile them individually.

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