Journal of the American Chemical Society

Synthesis of 7-Indolecarboxylic Acid1

H Singer, W Shive

Index: Singer; Shive Journal of the American Chemical Society, 1955 , vol. 77, p. 5700

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Citation Number: 17

Abstract

The inhibitory effect of 5-methyltryptophan on growth of Lactobacillus plantarum 8293 is prevented competitively by anthranilic acid, but both indole and tryptophan at relatively low concentrations reverse the toxicity of the methyltryptophan noncompetiti~ ely.~ Among possible explanations for these results, including the possibility that 5-methyltryptophan inhibits the conversion of anthranilic acid to indole, one alternative explanation was ...