Synthesis of high specific radioactivity [3H] emodin

A Hadj??Hamdri, A Vidal??Cros, M Gaudry…

Index: Hadj-Hamdri; Vidal-Cros; Gaudry; Sobrio; Rousseau Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 8 p. 795 - 799

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Citation Number: 4

Abstract

Key Words : emodin, NADPH dependent reductase, chrysophanol ... S umnm r y . Emodin, a precursor of chrysophanol in the biosynthesis of cynodontin by Pyrenochaefa rerrestris, has been tritiated with a high specific radioactivity (12.5 Ci/mmol) by hydrogenolysis of bromomethyl emodin. ... Introduction. An important step of the biosynthesis of cynodontin 1 (1) by Pyrenochaefa ferresfris is the transformation of emodin 2 into chrysophanol 3 (2) (Scheme 1). The ...