Intra/intermolecular direct allylic alkylation via Pd (II)-catalyzed allylic C− H activation

S Lin, CX Song, GX Cai, WH Wang…

Index: Lin, Song; Song, Chun-Xiao; Cai, Gui-Xin; Wang, Wen-Hua; Shi, Zhang-Jie Journal of the American Chemical Society, 2008 , vol. 130, p. 12901 - 12903

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Citation Number: 154

Abstract

Very recently, White and co-workers made significant progresses in the allylic C−O/N formation via Pd(II)-catalyzed C−H activation.(7) Liu and co-workers also reported a Pd(II)-catalyzed oxidative amination of allylic C−H bond.(8) During these processes, allylpalladium species 1 was proposed as the key intermediate. We envisioned that allylpalladium species 1 may also serve as an intermediate in direct allylic alkylation. To the best of our knowledge, direct alkylation of allylic C−H via ...