Journal of medicinal chemistry

Inhibition of tyrosinase-catalyzed melanin formation by catechol phenyl sulfones

JF Siuda, A Habal

Index: Siuda; Habal Journal of Medicinal Chemistry, 1974 , vol. 17, # 11 p. 1173 - 1177

Full Text: HTML

Citation Number: 0

Abstract

Catechol phenyl sulfones were synthesized and evaluated as potential inhibitors of tyrosinase-mediated Dopa melanin formation. The results suggest that the dopamine analogs, 2, 3-dikiydroxy-5-(@-aminoethyl) diphenyl sulfone hydrochloride (9b) and 2, 3-