Efficient Dibenzo [c] acridine Helicene-like Synthesis and Resolution: Scaleup, Structural Control, and High Chiroptical Properties

L Jierry, S Harthong, C Aronica, JC Mulatier, L Guy…

Index: Jierry, Loic; Harthong, Steven; Aronica, Christophe; Mulatier, Jean-Christophe; Guy, Laure; Guy, Stephan Organic Letters, 2012 , vol. 14, # 1 p. 288 - 291

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Citation Number: 16

Abstract

Herein, we describe our recent expeditious synthesis of dibenzo [c] acridine helicene-like compounds on a large scale in pure enantiomeric form. This flexible synthesis allows for variation at several positions on the skeleton. Geometrical parameters related to these compounds have been obtained from monocrystal X-ray structure resolution. Additionally, chiroptical parameters have been recorded, highlighting the versatility of this family ...