A Highly Efficient and Convenient Method for the Direct Conversion of Alkyl THP Ethers into the Corresponding Alkyl Benzyl Ethers
T Suzuki, K Ohashi, T Oriyama
Index: Suzuki, Takeshi; Ohashi, Kousaburo; Oriyama, Takeshi Synthesis, 1999 , # 9 p. 1561 - 1563
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Citation Number: 17
Abstract
Abstract: Direct conversion of alcohol tetrahydropyranyl (THP) ethers into the corresponding benzyl ethers can be conveniently performed by reaction with triethylsilane and benzaldehyde in the presence of a catalytic amount of trimethylsilyl trifluoromethanesulfonate (TMSOTf) in a one-pot procedure. Key words: THP ethers, benzyl ethers, triethylsilane, benzaldehyde, one-step conversion of protecting group
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