Tetrahedron Letters

Synthesis of nitrogen heterocycles via palladium-catalyzed intramolecular cyclization

RC Larock, S Babu

Index: Larock, Richard C.; Babu, Srinivasan Tetrahedron Letters, 1987 , vol. 28, # 44 p. 5291 - 5294

Full Text: HTML

Citation Number: 193

Abstract

Catalytic amounts of Pd(OAc) 2 in the presence of -Bu 4 NCl, DMF and an appropriate base (Na 2 CO 3 , (NaOAc or Et 3 N) cyclize nitrogen-containing -iodoaryl alkenes to indoles, indolines,3 oxindoles, quinolines, isoquinolines and isoquinolones in short reaction times, under mild temperatures, and in high yields. ... Catalytic amounts of palladium efficiently cyclize nitrogen-containing -iodoaryl alkenes to indoles, indolines, oxindoles, quinolines, ...

Related Articles:

Construction of Erythrinane Skeleton via Pd (0)-Catalyzed Intramolecular Dearomatization of para-Aminophenols

[Bedford, Robin B.; Fey, Natalie; Haddow, Mairi F.; Sankey, Rosalind F. Chemical Communications, 2011 , vol. 47, # 12 p. 3649 - 3651]

Synthesis of α, β-Unsaturated Aldehydes Based on a One-Pot Phase-Switch Dehydrogenative Cross-Coupling of Primary Alcohols

[Porcheddu, Andrea; Mura, Manuel G.; De Luca, Lidia; Pizzetti, Marianna; Taddei, Maurizio Organic Letters, 2012 , vol. 14, # 23 p. 6112 - 6115]

N-Tosylhydrazine-mediated deoxygenative hydrogenation of aldehydes and ketones catalyzed by Pd/C

[Tetrahedron, , vol. 69, # 30 p. 6083 - 6087]

Synthesis of Functionalized Indole??and Benzo??Fused Heterocyclic Derivatives through Anionic Benzyne Cyclization

[Barluenga, Jose; Fananas, Francisco J.; Sanz, Roberto; Fernandez, Yolanda Chemistry - A European Journal, 2002 , vol. 8, # 9 p. 2034 - 2046]

Formation of Cyclohepta [b] indole Scaffolds via Heck Cyclization: A Strategy for Structural Analogues of Ervatamine Group of Indole Alkaloid

[Fraile, Jose M.; Le Jeune, Karel; Mayoral, Jose A.; Ravasio, Nicoletta; Zaccheria, Federica Organic and Biomolecular Chemistry, 2013 , vol. 11, # 26 p. 4327 - 4332]

More Articles...