α-Halogenation of Secondary Nitriles1, 2

CL Stevens, TH Coffield

Index: Stevens; Coffield Journal of the American Chemical Society, 1951 , vol. 73, p. 103

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Citation Number: 23

Abstract

Summary A pungent isobutylamide of an unsaturated CIS acid has been isolated from the roots of Helwpsis scabra Dunal. The substance, for which the name" scabrin" is proposed, is appreciably more toxic than the pyrethrins to house flies. Hydrogenation of the amide gave N-isobutylstearamide, and on oxidation it yielded butyric, oxalic, succinic and N- isobutyloxamic acids. On the basis of these degradations and of its ultraviolet absorption ...