ZnI2/NaCNBH3 as an efficient reagent for regioselective ring opening of the benzylic epoxide moiety

LM Finkielsztein, JM Aguirre, B Lantano…

Index: Finkielsztein; Aguirre; Lantano; Alesso; Moltrasio Iglesias Synthetic Communications, 2004 , vol. 34, # 5 p. 895 - 901

Full Text: HTML

Citation Number: 7

Abstract

View all references we needed to reduce α??chloroketone 1 to the indanic compound 2 (Fig. 1). To this end, we chose sodium cyanoborohydride in the presence of zinc iodide. This system afford reductive deoxygenation of aryl aldehydes and ketones22. Lau , CK , Dufresne , C. , Bélanger , PC , Piétré , S. and Scheigetz , J. 1986. Reductive deoxygenation of aryl aldehydes and ketones and benzylic, allylic, and tertiary alcohols by ZnI2??NaCNBH3. J. Org. Chem., 51(15): ...