Aminoalkylamides and Oxazolidinediones1

SL Shapiro, IM Rose, L Freedman

Index: Shapiro et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 3083,3084

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Citation Number: 13

Abstract

B series of a-hydroxyamides of the type I and the derived oxazolidinediones of the type I1 have been examined for central nervous system depressant effects. Many compounds showed significant activity. A new and convenient prwess for synthesis of oxazolidinediones of the type I1 in one step from the a-hydroxyester, the dialkylaminoalkylamine and diethyl carbonate is described.