Esterification using a polymer-supported phosphine reagent

RA Amos, RW Emblidge, N Havens

Index: Amos, Richard A.; Emblidge, Robert W.; Havens, Nick Journal of Organic Chemistry, 1983 , vol. 48, # 20 p. 3598 - 3600

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Citation Number: 66

Abstract

Pursuant to our interest in developing macrolide cyclization techniques which avoid high- dilution requirements, we have investigated the use of a polymer-supported reagent for the preparation of a wide variety of esters. The use of triphenylphosphine and diethyl azodicarboxylate (DEAD) has become well established as a means of formation of esters from alcohols and acids' and of macrolides from precursor w-hydroxy acids. 2 The use of ...