H-Tetraoxaspirophosphoranes as possible intermediates in the phosphonylation by phosphorous acid/oxiranes

SB Tzokov, NG Vassilev, RT Momtcheva…

Index: Tzokov, Svetomir B.; Vassilev, Nikolay G.; Momtcheva, Rositza T.; Kaneti, Jose; Petkov, Dimiter D. Phosphorus, Sulfur and Silicon and Related Elements, 2000 , vol. 166, p. 187 - 196

Full Text: HTML

Citation Number: 9

Abstract

Abstract The detailed 31P-NMR study of the mechanism of the ribozymomimetic phosphonylation with phosphorous acid/oxirane revealed consecutive formation of β- hydroxy H-phosphonate monoester, di-(β-hydroxyalkyl) H-phosphonate, alkylene H- phosphonate. β-hydroxyalkyl alkylene phosphite and the corresponding stereoelectronically stabilized pentacoordinated H-tetraoxaspirophosphorane. The equilibrium between the ...