Structure-activity relations in psychotomimetic phenylalkylamines

FAB Aldous, BC Barrass, K Brewster…

Index: Aldous,F.A.B. et al. Journal of Medicinal Chemistry, 1974 , vol. 17, p. 1100 - 1111

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Citation Number: 80

Abstract

1100 Journal ofMedicinal Chemistry, 2974, Vol. 27, No. 20 Pinder, et al. tected with a drying tube. A solution of phosgene (55 ml, 12.5% in benzene) was then added with vigorous stirring. The reaction was cooled for an additional 10 min and was then kept at room temperature for 1 hr. The reaction mixture was cooled again, treated with 100-ml portions of 1 N HCl until free of amine, and then rinsed successively with 8% NaHCOs and water, ...