Organic & biomolecular chemistry

… with tert-butylamine: demonstration of a phosphonamidic-sulfonic anhydride intermediate and 18 O-labelling evidence on how it may be formed 1

MJP Harger

Index: Harger, Martin J.P. Organic and Biomolecular Chemistry, 2003 , vol. 1, # 19 p. 3390 - 3395

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Citation Number: 4

Abstract

Reaction of R (Ph) P (O) NHOSO2Bn (R= PhMeCH) with ButNH2 in CH2Cl2 gives a mixture of RP (O)(NHPh) NHBut and ButNHSO2Bn, the proportion of the sulfonamide increasing steadily (14.6% to 32.9%) as the concentration of amine is reduced (8.0 to 0.2 mol dm− 3).

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