Journal of the American Chemical Society

Physiologically Active Phenethylamines Containing a Tertiary Hydroxyl

CM Suter, AW Weston

Index: Suter; Weston Journal of the American Chemical Society, 1942 , vol. 64, p. 2451

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Citation Number: 2

Abstract

It has been found that the introduction of an alkyl group into the beta position of phenethylamines2 or a-methylphenethylamine~~ lowers the toxicity without appreciably affecting the physiological action. The extension of this study to include the effect of alkylating the carbon atom tearing the hydroxyl in amines of the type CeH&H (OH) CH (R) NHR (R is H or CH3) seemed of interest.