Decreased catecholamine sensitivity and β-adrenergic-receptor density in failing human hearts

MR Bristow, R Ginsburg, W Minobe…

Index: Steffens; Schunack Archiv der Pharmazie, 1987 , vol. 320, # 2 p. 135 - 140

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Citation Number: 2397

Abstract

... by incubating 300 μl of the membrane preparation with six to eight increasing concentrations of [ 3 H]DHA (1.1 to 11.0 nM in most cases) in the presence or absence of 10 –3 M L-isoproterenol, in a total volume of 450 μl. ... 2. ... 1963; 34:320–4. CrossRef | Web of Science | Medline. 9. ...