Synthetic communications

Syntheses of 4-(3, 5-Bisphenylmethylene-4-oxo-piperidin-1-yl)-4-oxo-but-2 Z-enoic Acid Arylamides as Candidate Cytotoxic Agents

A Jha, JR Dimmock

Index: Jha, Amitabh; Dimmock, Jonathan R. Synthetic Communications, 2003 , vol. 33, # 7 p. 1211 - 1223

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Citation Number: 10

Abstract

Abstract The title compounds were designed and synthesized as candidate cytotoxic agents. They were synthesized by reacting 3, 5-bisphenylmethylene-piperidin-4-one with the appropriate 3-arylcarbamoyl-acrylic acids. These reactions follow an unusual mechanism