Design, synthesis and antioxidant properties of ovothiol-derived 4-mercaptoimidazoles

V Zoete, F Bailly, JP Catteau, JL Bernier

Index: Zoete, Vincent; Bailly, Fabrice; Catteau, Jean-Pierre; Bernier, Jean-Luc Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 20 p. 2983 - 2988

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Citation Number: 28

Abstract

Fourteen 4-mercaptoimidazoles derived from the naturally occurring family of antioxidants, the ovothiols, have been synthesized by cyclization of thioamides with trimethylsilyl trifluoromethanesulfonate (triflate). These compounds have been assayed for their radical- scavenging activity.