Synthetic and structural studies of some chloro??substituted methyl 2, 1??benzisoxazole??3??carboxylates and related compounds

TJ Mccord, DR Smith, JK Swan…

Index: McCord,T.J. et al. Journal of Heterocyclic Chemistry, 1979 , vol. 16, p. 1249 - 1252

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Citation Number: 3

Abstract

Abstract Methyl 5-chloro-and 5, 7-dichloro-2, 1-benzisoxazole-3-carboxylates have been synthesized by treatment of o-nitromandelic and 5-chloro-2-nitroamandelic methyl esters, respectively, with thionyl chloride under appropriate reaction conditions. The structural assignments of both heterocyclic products were based on elemental and spectral analyses, and their conversion to the corresponding 5-chloro-and 5, 7-dichloro substituted 2, 1- ...