Die Pharmazie

Synthesis of some new phenothiazine derivatives of expected medicinal value.

H Abu-Shady, YM Dessouky, MK El-Said

Index: Abu-Shady,H. et al. Pharmazie, 1976 , vol. 31, # 1 p. 18 - 20

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Abstract

2-Chloroacetyl phenothiazines were reacted with certain phenols and salts of some acids under different conditions to yield 2-substituted acetylphenothiazines. Another series of 10- substituted phenothiazines was synthesized by treatment of 10-chloroacetylphenothiazine with either the appropriate amines or salts of the respective acids. The optimum experimental conditions for the preparation of 2-chloroacetyl-10-acetyl-phenothiazine by ...