Electrochemical determination of the pKa of weak acids in N, N-dimethylformamide

…, D Celadon, MG Severin, E Vianello

Index: Maran, Flavio; Celadon, Dino; Severin, Maria Gabriella; Vianello, Elio Journal of the American Chemical Society, 1991 , vol. 113, # 24 p. 9320 - 9329

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Citation Number: 91

Abstract

Abstract: The electroreduction of NH-protic a-bromo amides in DMF generates an enolate- type base which undergoes a fast proton transfer from the parent compound (self- protonation), affording the corresponding reduced amide together with the conjugate base of the bromo amide. When an acid weaker than the bromo amide is added to the solution, a current increase in a potential region more negative than the main voltammetric reduction ...