Synthesis of analogues of antihyperglycemic lead karanjin
PP Yadav, AK Srivastava, R Maurya
Index: Akanksha; Yadav, Prem P.; Srivastava, Arvind K.; Maurya, Rakesh Medicinal Chemistry Research, 2011 , vol. 20, # 9 p. 1465 - 1472
Full Text: HTML
Citation Number: 2
Abstract
Abstract Karanjin isolated in gram scale from Pongamia pinnata was subjected to transformation reactions and 11 analogues were prepared and evaluated for their antihyperglycemic activity in streptozotocin-induced diabetic rats, and compared with the standard drug metformin at the dose of 100 mg/kg body weight. Four derivatives showed comparable activity with metformin.
Related Articles:
[Yang, Yang; Cui, Xi-Kai; Zhong, Ming; Li, Zhong-Jun Carbohydrate Research, 2012 , vol. 361, p. 189 - 194]
Synthesis of β-glycosyl amides from N-glycosyl dinitrobenzenesulfonamides
[Gaitonde, Vishwanath; Sucheck, Steven J. Journal of Carbohydrate Chemistry, 2012 , vol. 31, # 4-6 p. 353 - 370]
[Tojino, Mami; Hirose, Yuriko; Mizuno, Mamoru Tetrahedron Letters, 2013 , vol. 54, # 52 p. 7124 - 7126]
[Tetrahedron Letters, , vol. 54, # 52 p. 7124 - 7126]
[Tojino, Mami; Hirose, Yuriko; Mizuno, Mamoru Tetrahedron Letters, 2013 , vol. 54, # 52 p. 7124 - 7126]