Journal of the American Chemical Society

Synthesis of Structures Related to Bacitracin A

W Stoffel, LC Craig

Index: Stoffel,W.; Craig,L.C. Journal of the American Chemical Society, 1961 , vol. 83, p. 145 - 149

Full Text: HTML

Citation Number: 27

Abstract

When all the available evidence for the structure of bacitracin A is considered, the most probable one is that shown in Fig. l. 1-4 It would seem most likely that a linear dodecapeptide is first synthesized by the organism and that two rings are then formed as shown in Fig. 2. The thiazoline ring is now well e~ tablished,~~ but direct evidence for the linkage connecting the aspartyl-P-carboxyl group and the 6-amino-nitrogen of the lysine ...