Tetrahedron

Catalytic guanylation of aliphatic, aromatic, heterocyclic primary and secondary amines using nanocrystalline zinc (II) oxide

ML Kantam, S Priyadarshini, PJA Joseph, P Srinivas…

Index: Kantam, M. Lakshmi; Priyadarshini; Amal Joseph; Srinivas; Vinu; Klabunde; Nishina, Yuta Tetrahedron, 2012 , vol. 68, # 29 p. 5730 - 5737

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Citation Number: 15

Abstract

Nanocrystalline ZnO was found to be a highly efficient heterogeneous catalyst for the guanylation of amines with various carbodiimides to afford N, N′, N ″-trisubstituted guanidines in excellent yields. Structurally divergent aliphatic, aromatic, heterocyclic primary and secondary amines were converted to the corresponding N, N′, N ″-trisubstituted guanidines using optimal conditions. The catalyst was easy to handle even under ...