Iridium diamine catalyst for the asymmetric transfer hydrogenation of ketones

H Vázquez??Villa, S Reber, MA Ariger…

Index: Vazquez-Villa, Henar; Reber, Stefan; Ariger, Martin A.; Carreira, Erick M. Angewandte Chemie - International Edition, 2011 , vol. 50, # 38 p. 8979 - 8981

Full Text: HTML

Citation Number: 46

Abstract

Catalytic asymmetric transfer hydrogenation (ATH) of ketones has emerged as an attractive alternative to the use of hydrogen for the preparation of optically active secondary alcohols.[1] The majority of the research carried out in this area has relied on RuII catalysts bearing optically active phosphines and amino/sulfonamides.[1] Among the most widely employed catalytic systems is that of Noyori et al., namely the RuII–TsDPEN catalyst ( ...