Helvetica Chimica Acta

Über atropisomere Biphenyl??Derivate mit einer Pseudoasymmetrieachse

G Helmchen, V Prelog

Index: Helmchen,G.; Prelog,V. Helvetica Chimica Acta, 1972 , vol. 55, p. 2599 - 2611

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Citation Number: 20

Abstract

Abstract Diastereomeric biphenyl derivatives VIIIa and b have been prepared as first examples of compounds with an axis of pseudoasymmetry. Compound VIIIa was prepared by an unambiguous synthesis from (+)-V. The absolute configuration of the latter was determined by correlation with (+)-(R)-2-amino-2′, 6-dimethyl-6′-nitro-biphenyl (XII) and hence the configuration of VIIIa (and therefore also of VIII b) was established.