Total synthesis of colchicine modelled on a biogenetic theory
AI Scott, F McCapra, RL Buchanan, AC Day…
Index: Scott,A.I. et al. Tetrahedron, 1965 , vol. 21, p. 3605 - 3631
Full Text: HTML
Citation Number: 39
Abstract
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A five step synthesis of desacetamidocolchiceine (XLVI) is described in which rings A and C are joined by oxidative coupling of the tropolone system. This completes a biogenetic-type total synthesis of colchicine (I). ... For early reports on medicinal and physiological effects of ...
Related Articles:
[Maurin, Cedric; Lion, Cedric; Bailly, Fabrice; Touati, Nadia; Vezin, Herve; Mbemba, Gladys; Mouscadet, Jean Franois; Debyser, Zeger; Witvrouw, Myriam; Cotelle, Philippe Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 14 p. 5194 - 5201]