Liposomal membranes. 2. Synthesis of a novel pyrene-labeled lecithin and structural studies on liposomal bilayers

J Sunamoto, H Kondo, T Nomura…

Index: Sunamoto, Junzo; Kondo, Hiroki; Nomura, Tadashi; Okamoto, Hiroshi Journal of the American Chemical Society, 1980 , vol. 102, # 3 p. 1146 - 1152

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Citation Number: 56

Abstract

(DPDL), was synthesized for use in structural studies on the liposomal bilayers. From the fluorescence measurements on DPDL incorporated into the phospholipid bilayers as well as in organic solvents and aqueous buffered solutions, the following interesting information was obtained.(I) The probe DPDL is intercalated in a well-ordered fashion in the very hydrophobic domain of egg and dipalmitoylphosphatidylcholine bilayers.(2) Without ...