Semisynthetic penicillins. I. 2-biphenylylpenicillins

JRE Hoover, AW Chow, RJ Stedman…

Index: Hoover,J.R.E. et al. J. Med. Chem., 1964 , vol. 7, # 3 p. 245 - 251

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Citation Number: 18

Abstract

The preparation of a number of penicillins with 2-biphenylyl side chains is described. Some of the substituted 2-biphenylcarboxylic acids used as intermediates were synthesized for the first time or were prepared by new methods. These penicillins were active against penicillin<;-resistant as well as penicillin G-susreptible staphylococci.