Vilsmeier–Haack formylation of acetonitrile revisited: Synthesis of novel pyrazolo [1, 5??a] pyrimidines and triazolo [1, 5??a] pyrimidine

MG Ghagare, DR Birari, DP Shelar…

Index: Ghagare, Maruti G.; Birari, Dilip R.; Shelar, Deepak P.; Toche, Raghunath B.; Jachak, Madhukar N. Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 2 p. 327 - 331

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Citation Number: 8

Abstract

The synthesis of pyrazolo [1, 5-a] pyrimidines is a promising avenue of research owing to various bioactivities displayed by this class of compounds. They have been established as selective inhibitors of adenosine cyclic mono phosphate (cAMP) phosphodiesterase in vitro [1, 2]. In addition to this some of these compounds showed antischistosomal activity [3]. Another class of compounds,[1, 2, 4] triazolo [1, 5-a] pyrimidine derivatives are promising ...