Structural characterization of two novel potential anticholinesterasic agents

…, F Wiectzycosky, EA Basso, RAC Gonçalves…

Index: Oliveira, Paulo R.; Wiectzycosky, Franciele; Basso, Ernani A.; Goncalves, Regina A.C.; Pontes, Rodrigo M. Journal of Molecular Structure, 2003 , vol. 657, # 1-3 p. 191 - 198

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Citation Number: 9

Abstract

Two novel compounds with possible anticholinesterase activity have been synthesized containing a carbamate and a dimethylamine group in 1, 2-positions of a cyclohexane ring (cis and trans isomers). Conformer populations were established by a combination of NMR 1H coupling constant analysis and DFT (B3LYP/6-311+ G (d, p)) calculations. 13C chemical shifts were calculated in order to confirm signal attributions. The cis isomer adopts a ...