The Mechanisms of the Fries Reaction1

R Baltzly, WS Ide, AP Phillips

Index: Baltzly et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 2522,2526

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Citation Number: 36

Abstract

The Fries reactioii is interpreted as proceeding through a complex of phenol ester and aluminum chloride which, when suf-ficiently polarized, becomes capable of acylating a different molecule or of rearranging. The former process follows the usual rules of orientation while the latter affords only o-hydroxy ketone As a rule the rearrangement is favored only at high temperatures, but it is facilitated by electron-repelling groups in the phenolic portion ...