Journal of medicinal chemistry

Compounds Related to Carnitine: Derivatives of 4-Dimethylamino-3-hydroxybutyric Acid

F Keller, RR Engle, MW Klohs

Index: Keller,F. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 202 - 203

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Citation Number: 5

Abstract

Condensation reactions involving the carboxamido group of tetracycline have been reported hy Gottstein, et a/.! These workers describe an xanthydrol condensate of tetracycline as well as numerous derivatives prepared from amines and formaldehyde by the Einhorn reaction. One of these, S-(pyrrolidi~ iomcthyl)-tetr:~-(yc'line, 2 has proved superior to tetracyclinc when administered parenterally.? 4