Phytochemistry

Biotransformation of hydrocortisone by a natural isolate of Nostoc muscorum

MT Yazdi, H Arabi, MA Faramarzi, Y Ghasemi, M Amini…

Index: Yazdi, Mojtaba Tabatabaei; Arabi, Homeira; Faramarzi, Mohammad Ali; Ghasemi, Younes; Amini, Mohsen; Shokravi, Shadman; Mohseni, Farzaneh Aziz Phytochemistry, 2004 , vol. 65, # 15 p. 2205 - 2209

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Citation Number: 25

Abstract

Hydrocortisone was converted in the culture of an isolated strain of the cyanobacterium Nostoc muscorum PTCC 1636 into some androstane and pregnane derivatives. The microorganism was isolated during a screening program from soil samples collected from paddy fields of north of Iran. The bioproducts obtained were purified using chromatographic methods and identified as 11β-hydroxytestosterone, 11β-hydroxyandrost-4-en-3, 17-dione ...