Freidel-crafts acylation of 1-tert-butyldimethylsilylpyrrole, a very short and simple route to 3-substituted pyrroles.
G Simchen, MW Majchrzak
Index: Simchen, Gerhard; Majchrzak, Michal W. Tetrahedron Letters, 1985 , vol. 26, # 41 p. 5035 - 5036
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Citation Number: 22
Abstract
... Gerhard Simchen*, Michal W. Majchrzak1 Institut f Organische Chemie, Biochemie und Isotopen forschung der Universit Stuttgart Pfaffenwaldring 55, D 7000 Stuttgart 80 Abstract: 1 -tertutyldimethylsilylpyrrOle undergoes Friedel-Crafts acylation almost exclusively at sosition giving after sodium fluoride sup- ported hydrolysis the 3yrruloketones. ... 3) U. Frick, G. Simchen, Synthesis 1984, 929. 4) MW Majchrzak, G. Simchen, J. Org. Chem. (submitted). ...
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