An efficient synthesis of O, O-Di Propyl (E)-2-[1-methyl 2-oxopropylidene] phosphorohydrazidothiolate (E) Oxime and Its Analogues: A Potential Marine Toxin

…, DK Dubey, BD Parashar, MP Kaushik

Index: Gupta, Arvind K.; Dubey; Parashar; Kaushik Phosphorus, Sulfur and Silicon and the Related Elements, 2008 , vol. 183, # 8 p. 1892 - 1910

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Citation Number: 23

Abstract

An efficient method for the synthesis of Ptychodiscus brevis toxin O, O-di n-propyl (E)-2-[1- methyl 2-oxopropylidene] phosphorohydrazidothiolate (E) oxime (TG-1) and its analogues has been developed using thermally stable and recyclable silica gel and Na2SO4 as a condensing agent and water scavenger, respectively. The compounds were evaluated against fish Rasbora daniconius by determining the LC50 and LC90 values. The results of ...