Requirements for Stereospecificity in Hydrolysis by α-Chymotrypsin. IV. The Hydroxyl Substituent. Absolute Configurations1

SG Cohen, E Khedouri

Index: Journal of the American Chemical Society, , vol. 83, p. 4228 - 4233

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Citation Number: 48

Abstract

... led to the following analysis : (1) The @-aryl and a-acylamido substit- uents of typical substrates for a-chymotrypsin6 are important for high chemical reactivity but ... which lead to this specificity and thus, in part at least, to the hydro- lytic action, it has seemed to us desirable to ... Vol. ...