gem-(Difluoroallyl) lithium: Preparation by lithium-halogen exchange and utilization in organosilicon and organic synthesis

D Seyferth, RM Simon, DJ Sepelak…

Index: Seyferth; Simon; Sepelak; Klein Journal of the American Chemical Society, 1983 , vol. 105, # 14 p. 4634 - 4639

Full Text: HTML

Citation Number: 69

Abstract

Abstract: gem-(Difluoroally1) lithium may be generated by lithium-bromine exchange between n-butyllithium and CH2= CHCF2Br at-95 “C by using an in situ procedure. When this Li [CF2CHCH2] preparation is carried out in the presence of chlorosilanes, aldehydes, ketones, and esters, products of the type R 3 S i CF 2 CH 4 H 2, RCH (OH) CF2CH== CH2, and RR'C (OH) CF2CH= CH2, respectively, are formed, often in good yield. The factors ...