Tetrahedron letters

A palladium-catalyzed carbonylative route to primary amides

E Morera, G Ortar

Index: Morera, Enrico; Ortar, Giorgio Tetrahedron Letters, 1998 , vol. 39, # 18 p. 2835 - 2838

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Citation Number: 56

Abstract

The palladium-catalyzed reaction of aryl and vinyl iodides and triflates with carbon monoxide in the presence of hexamethyldisilazane followed by hydrolytic work-up affords aromatic and α, β-unsaturated primary amides in good to high yields under relatively mild conditions.

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