Tetrahedron

New organocopper reagents prepared utilizing highly reactive copper

RD Rieke, RM Wehmeyer, TC Wu, GW Ebert

Index: Rieke, Reuben D.; Wehmeyer, Richard M.; Wu, Tse-Chong; Ebert, Greg W. Tetrahedron, 1989 , vol. 45, # 2 p. 443 - 454

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Citation Number: 62

Abstract

Highly reactive copper solutions have been prepared by the lithium naphthalide reduction of copper (I) iodide/trialkylphosphine complexes. These activated copper solutions will react with organic halides under very mild conditions to form stable organocopper reagents. Significantly, the organocopper reagents can contain considerable functionalities such as ester, nitrile, chloride, epoxide, and ketone groups. These functionalized organocopper ...

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