Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists

A Vasudevan, AJ Souers, JC Freeman…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 23 p. 5293 - 5297

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Citation Number: 45

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 5. We have previously reported the identification of MCHr1 antagonists based on a benzamide scaffold, 1. 6 Subsequent optimization led to the identification of ortho amino benzamides 2. 7 In this Letter, we describe our continuing ...