Dimethylpyridin-4-ylamine-catalysed alcoholysis of 2-amino-N, N, N-trimethyl-9H-purine-6-ylammonium chloride: An effective route to O6-substituted guanine …

R Schirrmacher, B Wängler, E Schirrmacher…

Index: Synthesis, , # 4 p. 538 - 542

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Citation Number: 20

Abstract

... [2] for the synthesis of O 6 -benzyl guanine. Annulation of an imidazole ring to 6-(benzyloxy)-2, 4,5-triaminopyrimidine at 180 °C was applied by Robins et al. [3] The O 6 -substituted guanines so far described [4] have usually been synthesized rather inefficiently by the former ...