Synthesis of novel analogs of acetyl coenzyme A: mimics of enzyme reaction intermediates

…, RT Bibart, DG Drueckhammer

Index: Martin, David P.; Bibart, Richard T.; Drueckhammer, Dale G. Journal of the American Chemical Society, 1994 , vol. 116, # 11 p. 4660 - 4668

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Citation Number: 46

Abstract

Abstract: An improved method for the synthesis of analogs of coenzyme A (CoA) and its thioesters, which are modified in the thiol or thioester moiety, has been developed using a combination of chemical and enzymatic reactions. The enzymes catalyzing the last two ...