An alternative synthesis of (+)??sesbanimide A

WJ Vloon, JC Van den Bos, NP Willard…

Index: Vloon, W. J.; Bos, J. C. van den; Willard, N. P.; Koomen, G.-J.; Pandit, U. K. Recueil des Travaux Chimiques des Pays-Bas, 1991 , vol. 110, # 10 p. 414 - 419

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Citation Number: 6

Abstract

Abstract D-(+)-xylose has been converted to (+)-sesbanimide A in sixteen steps. The synthetic scheme involves an unusual tricyclic silylated derivative (9a) of the monobenzoylated product of the earlier described glutarimide intermediate (7). Compound 9a is a pivotal intermediate for the construction of ring C of (+)-sesbanimide A.